Alan D Irvine Selected Research

Interleukin-9 (Interleukin 9)

10/2019

Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.

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Alan D Irvine Research Topics

Disease

73	Atopic Dermatitis (Atopic Eczema) 12/2024 - 04/2006
19	Eczema 11/2023 - 03/2007
12	Asthma (Bronchial Asthma) 01/2023 - 06/2006
10	Inflammation (Inflammations) 01/2022 - 10/2008
9	Ichthyosis Vulgaris (Dominant Ichthyosis Vulgaris) 06/2016 - 03/2006
6	Dermatitis 05/2022 - 10/2013
4	Skin Diseases (Skin Disease) 02/2024 - 05/2008
4	COVID-19 09/2023 - 01/2021
4	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2023 - 08/2007
4	Ichthyosis (Xeroderma) 01/2018 - 10/2002
3	Neoplasms (Cancer) 01/2024 - 01/2021
3	Infections 01/2024 - 10/2017
3	Hypersensitivity (Allergy) 10/2023 - 10/2013
3	Alopecia Areata 09/2023 - 07/2020
3	Allergic Rhinitis 01/2023 - 02/2013
3	Food Hypersensitivity (Food Allergy) 11/2018 - 02/2013
2	Pruritus (Itching) 12/2024 - 01/2023
2	Urticaria (Hives) 04/2024 - 01/2007
2	Venous Thromboembolism 01/2024 - 11/2022
2	Conjunctivitis 03/2023 - 01/2023
2	Exanthema (Rash) 01/2023 - 09/2012
2	Dysbiosis 01/2023 - 01/2018
2	Nasopharyngitis 01/2023 - 01/2021
2	Herpes Zoster 01/2023 - 11/2022
2	Necrosis 11/2022 - 01/2021
2	Alopecia (Baldness) 01/2021 - 02/2009
2	Iron Deficiencies 01/2021 - 01/2017
2	Warts (Wart) 11/2020 - 05/2008
2	Vitamin D Deficiency 03/2018 - 01/2017
2	Weight Gain 01/2018 - 11/2016
2	Peanut Hypersensitivity (Peanut Allergy) 07/2013 - 03/2011
1	Chronic Urticaria 04/2024
1	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2023
1	Localized Scleroderma (Morphea) 09/2023
1	Allergic Contact Dermatitis 03/2023
1	Rheumatoid Arthritis 01/2023
1	Injection Site Reaction 01/2023
1	Skin Neoplasms (Skin Cancer) 01/2023
1	Ankylosing Spondylitis 01/2023
1	Melanoma (Melanoma, Malignant) 01/2023
1	Psoriatic Arthritis 01/2023
1	Herpes Simplex 11/2022
1	Rheumatic Diseases (Rheumatism) 11/2022
1	Hemangioma (Angioma) 06/2022

Drug/Important Bio-Agent (IBA)

47	Filaggrin ProteinsIBA 11/2023 - 03/2006
7	dupilumabIBA 12/2023 - 07/2021
7	CytokinesIBA 01/2023 - 04/2012
6	upadacitinibIBA 01/2024 - 01/2021
6	Immunoglobulin E (IgE)IBA 01/2023 - 02/2002
6	Proteins (Proteins, Gene)FDA Link 02/2014 - 02/2002
5	Methotrexate (Mexate)FDA LinkGeneric 02/2024 - 09/2017
4	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2018
4	baricitinibIBA 12/2023 - 11/2022
4	AllergensIBA 04/2016 - 10/2008
4	Keratins (Keratin)IBA 01/2011 - 01/2005
3	lebrikizumabIBA 12/2024 - 03/2023
3	Interleukin-13IBA 12/2024 - 10/2019
3	Janus Kinase InhibitorsIBA 12/2023 - 01/2021
3	Janus KinasesIBA 12/2023 - 01/2021
3	Cyclosporine (Ciclosporin)FDA LinkGeneric 11/2023 - 11/2013
3	Immunosuppressive Agents (Immunosuppressants)IBA 07/2021 - 01/2018
3	IronIBA 01/2021 - 01/2017
3	Vitamin D FDA LinkGeneric 11/2018 - 01/2017
2	Immunoglobulin A (IgA)IBA 12/2024 - 07/2023
2	Adrenal Cortex Hormones (Corticosteroids)IBA 02/2023 - 01/2021
2	Creatine Kinase (Creatine Phosphokinase)IBA 01/2023 - 01/2021
2	EmollientsIBA 01/2023 - 01/2023
2	Ferritins (Ferritin)IBA 01/2021 - 01/2018
2	Cidofovir (Vistide)FDA Link 11/2020 - 05/2008
2	InflammasomesIBA 01/2020 - 10/2019
2	hydroxide ionIBA 11/2018 - 01/2017
2	Desmoplakins (Desmoplakin)IBA 01/2018 - 11/2015
2	Interleukin-1 (Interleukin 1)IBA 11/2016 - 04/2012
2	Desmoglein 1IBA 11/2015 - 10/2013
2	Small Interfering RNA (siRNA)IBA 05/2014 - 01/2011
2	Serine Peptidase Inhibitor Kazal-Type 5IBA 09/2008 - 02/2002
1	Monoclonal AntibodiesIBA 12/2024
1	Omalizumab (Xolair)FDA Link 04/2024
1	anti-IgE antibodiesIBA 04/2024
1	Deoxyribonuclease I (Nickase)IBA 10/2023
1	RNA (Ribonucleic Acid)IBA 03/2023
1	Immunomodulating AgentsIBA 02/2023
1	tralokinumabIBA 01/2023
1	Chemokine CCL17IBA 01/2023
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 01/2023
1	omega-Chloroacetophenone (Mace)IBA 11/2022
1	tofacitinibIBA 11/2022
1	Propranolol (Inderal)FDA LinkGeneric 06/2022
1	LipidsIBA 01/2022
1	Glucosylceramidase (Glucocerebrosidase)IBA 01/2022
1	TYK2 Kinase (Tyrosine Kinase 2)IBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021

Therapy/Procedure

16	Therapeutics 04/2024 - 09/2013
2	Phototherapy (Light Therapy) 03/2023 - 10/2017
2	Immunomodulation 01/2021 - 01/2017
1	Withholding Treatment 11/2023
1	Aftercare (After-Treatment) 11/2023
1	Off-Label Use 09/2023
1	Skin Care 01/2023